Proteins

Protein Purification
Solid phase purification of proteins with a co-expressed tag greatly simplifies protein purification procedures for medium or high throughput demands. Careful treatment of the protein samples and reliable automation technology are essential for high recovery rates of native protein.

CyBio vacuum-based systems enable the control of vacuum strength to optimize elution conditions. CyBi^®-RoboSpense, equipped with our vacuum station enables purification after sample transfer from any tube or plate format.

Equipped with a magnetic bead separator and a gripper tool the 8-channel pipettor CyBi^®_-DiluS^pro is best suited for processing smaller sample numbers. CyBi^®_-RoboSpense provides the highest flexibility for variable sample numbers and plate and tube formats.

Protein crystallization
Highest precision pipetting at very low volumes and fast experiment setup to avoid evaporation are key factors for reproducible crystallization screenings. Based on CyBio's strength in precise and reliable automation our CyBi^®_-CrystalCreator allows easy, fast and safe setup of crystallization experiments. For job list-based production of crystallization liquids and aliquotting the CyBi®-RoboSpense is ideally suited.

Protein quantification, Enzyme Kinetics and ELISA’s
The CyBi^®-RoboSpense uses 4 or 8 variable spacing tips is best suited for processing individual samples invarious tube and plate formats. The CyBi^®_-Disk ideally performs sample processing in 96-, 384- and 1536- well plates. 

MALDI/TOF Target spotting
CyBio's CyBi^®_-Well, CyBi^®-Well vario and CyBi^®-Disk are suited to spot onto any target compatible with 96-well or 384-well microplates.

Structure determination of the virulence factor AsaP1 from Aeromonas salmonicida subsp. Achromogenes Precision of the 96-Channel Head of the CyBi^®-CrystalCreator
Example Data of Precise Liquid Handling in the Low Volume Range Using Different Pipetting Modes Precision of the 8-Channel Head of the CyBi^®-CrystalCreator
Example Data of Precise Liquid Handling in the Low Volume Range Using Different Pipetting Modes A Robust and Sensitive Automated Method for Mass Spectrometry-Based Serum Pattern Diagnostics using Well-Established ZipTip Technology CyBi^®-CrystalCreator Feeds Protein Structure Pipeline Tryptic Mapping Automated on the CyBi^®-RoboSpense and Integration of an Agilent 1100/1200 HPLC System for Peptide Analysis Fully automated sitting drop protein crystallization with CyBi^®-CrystalCreator using JBScreen Basic HTS Kit Non-denaturating multidimensional serum proteomics: Optimized method and applications Automation of protein crystallization in "sitting drop"