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The quality of assay results depends on multiple factors: the sensitivity, specificity and robustness of the assay technology, the quality of the reagents and the quality of the process execution. In drug discovery the importance of cellular assays is still increasing. A key factor to reliable process quality is automation as this ensures equal treatment of all samples. In addition, automation enables high throughput and low volume assays, offering significant time and cost savings. CyBio provides high performance automation for individual assay steps such as liquid handling and detection, as well as reliable scheduling and automation of the entire assay process.

Automated systems performing multiple or all assay steps are customized by CyBio to provide the optimal performance for the customer's assay, throughput and quality requirements. Through a combination of high-quality devices from CyBio and other suppliers, our Customized Solutions Team is able to provide powerful automation systems for all types of assays. Our experience includes the integration of more than 40 different devices such as readers, incubators, shakers, washers and centrifuges.

Application and Technical Notes

Reliable Automated Cytotoxicity Profiling for Chemistry Focused Laboratories by Combining Multiplexed Cytotoxicity Assays with the CyBi®-FeliX Liquid Handling Instrument Combining CyBi®-FeliX Automated Liquid Handling, Cell Health Assays and Frozen, Thaw-and-Use Cells Enables Automated Cytotoxicity Profiling Simplify complex pathway dissection by combining the power of HTRF® cellular phospho-assays and the flexibility of the CyBi®-FeliX liquid handling System Implementation of Cisbio's HTRF® M1 muscarinic receptor related assays on CyBio liquid handling solutions for small and high throughput Automated media exchange in the 3D in vitro pannus-model with the CyBi®-Disk workstation using 96-well plate format CyBi®-RoboSpense- Performance Characterization and Demonstration of Assay Optimization Capabilities Isolation and detection of Mycobacterium avium ssp. paratuberculosis in milk samples as automated on a CyBi®-RoboSpense ADME and cytotoxicity assays – Use of the CyBi®-Well for reagent addition and washing procedures Multiplexed Viability, Cytotoxicity and Apoptosis Assays for Cell-based Screening An Automated Bioluminescent Assay For Measuring Phosphodiesterase Activity Automation of Novel Assays for Cell-Based Multiplexing CyBi®-DiluSpro - Excellent Serial Dilution in 96 Well Microplates Automated TRANSIL® HSA Binding Kit on CyBi®-Well vario
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